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Invitrogen
Annexin A6 Recombinant Rabbit Monoclonal Antibody (K01_1M79)
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Product Details
MA563163
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_1M79
Immunogen
Recombinant protein of human Annexin VI (aa 2-100).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
50mM tris glycine, pH 7.4, with 40% glycerol, 150mM NaCl, 0.05% BSA
Contains
0.01% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AKPAQGAKYR GSIHDFPGFD PNQDAEALYT AMKGFGSDKE AILDIITSRS NRQRQEVCQS YKSLYGKDLI ADLKYELTGK FERLIVGLMR PPAYCDAKE
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%, Pig - 90%, Cynomolgus monkey - 98%.
Target Information
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 67 kDa calelectrin; Annexin A6; Annexin VI; annexin VI (p68); annexin VI, p68; Annexin-6; calcium-binding protein 65/67; calcium-binding protein CATA 65/67; calcium-binding protein p68; calelectrin; calphobindin II; Calphobindin-II; CBP 65/67; Chromobindin-20; CPB-II; Lipocortin VI; p68; p70; Protein III; testis secretory sperm-binding protein Li 198a; unnamed protein product
Gene Aliases: ANX6; ANXA6; AnxVI; AW107198; Cabm; Camb; CBP68; CPB-II; p68; p70
UniProt ID: (Human) P08133, (Mouse) P14824
Entrez Gene ID: (Human) 309, (Mouse) 11749, (Rat) 79125
phosphatidylserine binding
calcium ion binding
protein binding
GTP binding
calcium-dependent phospholipid binding
lipid binding
ligand-gated ion channel activity
cholesterol binding
identical protein binding
calcium-dependent protein binding
protein complex binding
protein homodimerization activity
calcium-binding protein
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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