Search
Invitrogen
EHD1 Recombinant Rabbit Monoclonal Antibody (K01_1Q63)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA563717
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_1Q63
Immunogen
A synthetic peptide of human EHD1.
Conjugate
Form
Liquid
Concentration
0.40 mg/mL
Amount
40 µg
Purification
Protein A/G
Storage buffer
50mM tris glycine, pH 7.4, with 150mM NaCl, 40% glycerol, 0.05% BSA
Contains
0.01% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. EHD1 also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Further, EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The EHD1 protein is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: EH domain-containing protein 1; hPAST1; mPAST1; PAST homolog 1; similar to Homo sapiens Hpast (HPAST) mRNA with GenBank Accession Number AF001434.1; Testilin; unnamed protein product
Gene Aliases: AA409636; CDABP0131; EHD1; H-PAST; HPAST1; PAST; PAST1; RGD1306960; RME-1
UniProt ID: (Human) Q9H4M9, (Mouse) Q9WVK4, (Rat) Q641Z6
Entrez Gene ID: (Human) 10938, (Mouse) 13660, (Rat) 293692
intracellular protein transport
endocytosis
positive regulation of cholesterol storage
positive regulation of neuron projection development
protein transport
endosomal transport
cell projection organization
neuron projection development
endocytic recycling
low-density lipoprotein particle clearance
cholesterol homeostasis
protein homooligomerization
cilium morphogenesis
protein localization to cilium
protein localization to plasma membrane
positive regulation of myoblast fusion
cellular response to nerve growth factor stimulus
positive regulation of endocytic recycling
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support