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Invitrogen
MST4 Recombinant Rabbit Monoclonal Antibody (K01_1U14)
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Product Details
MA563834
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_1U14
Immunogen
A synthetic peptide of human MST4 (aa 1-13).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
50mM tris glycine, pH 7.4, with 0.05% BSA, 150mM NaCl, 40% glycerol
Contains
0.01% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAHSPVAVQV PGM
Target Information
MST4 is member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternatively spliced; Mammalian STE20-like protein kinase 4; mammalian sterile 20-like 4; MST-4; MST3 and SOK1-related kinase; OTTHUMP00000215132; OTTHUMP00000215134; RP6-213H19.1; serine/threonine protein kinase 26; serine/threonine protein kinase MST4; Serine/threonine-protein kinase 26; Serine/threonine-protein kinase MASK; serine/threonine-protein kinase MST4; STE20-like kinase 4; STE20-like kinase MST4; unnamed protein product
Gene Aliases: MASK; MST4; RGD1563568; STK26
UniProt ID: (Human) Q9P289
Entrez Gene ID: (Human) 51765, (Rat) 317589
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
identical protein binding
protein homodimerization activity
metal ion binding
protein serine kinase activity
receptor signaling protein serine/threonine kinase activity
protein phosphorylation
apoptotic process
cellular response to starvation
negative regulation of cell migration
cellular response to oxidative stress
intracellular signal transduction
regulation of apoptotic process
protein autophosphorylation
positive regulation of microvillus assembly
signal transduction by protein phosphorylation
microvillus assembly
response to hydrogen peroxide
regulation of cell differentiation
regulation of hydrogen peroxide-induced cell death
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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