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Invitrogen
IL-1RAcP Recombinant Rabbit Monoclonal Antibody (K01_2M88)
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Product Details
MA564098
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_2M88
Immunogen
Recombinant protein of human IL-1RAcP (aa 21-367).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
50mM tris glycine, pH 7.4, with 0.05% BSA, 150mM NaCl, 40% glycerol
Contains
0.01% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SERCDDWGLD TMRQIQVFED EPARIKCPLF EHFLKFNYST AHSAGLTLIW YWTRQDRDLE EPINFRLPEN RISKEKDVLW FRPTLLNDTG NYTCMLRNTT YCSKVAFPLE VVQKDSCFNS PMKLPVHKLY IEYGIQRITC PNVDGYFPSS VKPTITWYMG CYKIQNFNNV IPEGMNLSFL IALISNNGNY TCVVTYPENG RTFHLTRTLT VKVVGSPKNA VPPVIHSPND HVVYEKEPGE ELLIPCTVYF SFLMDSRNEV WWTIDGKKPD DITIDVTINE SISHSRTEDE TRTQILSIKK VTSEDLKRSY VCHARSAKGE VAKAAKVKQK VPAPRYTVEL ACGFGAT
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%, Pig - 88%, Cynomolgus monkey - 99%.
Target Information
This gene encodes a component of the interleukin 1 receptor complex, which initiates signaling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytokine receptor; hide; IL 1R 3; IL 1R3; IL 1RAcP; IL 1RAP; IL-1 receptor accessory protein; IL-1R-3; IL-1RAcP; alternatively spliced; IL-1RAcPbeta; receptor accessory protein; IL1RAcP; ILN; Interleukin; Interleukin-1 receptor 3; Interleukin-1 receptor accessory protein; interleukin-1 receptor accessory protein beta; sIL-1RAcP; sIL-1RAcP-beta; alternatively spliced; sIL-1RAcP; alternatively spliced; unnamed protein product
Gene Aliases: C3orf13; IL-1RAcP; IL1R3; IL1RAP
UniProt ID: (Human) Q9NPH3
Entrez Gene ID: (Human) 3556
immune system process
inflammatory response
immune response
signal transduction
cytokine-mediated signaling pathway
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
positive regulation of interleukin-6 production
interleukin-33-mediated signaling pathway
innate immune response
positive regulation of synapse assembly
protein-containing complex assembly
interleukin-1-mediated signaling pathway
regulation of postsynaptic density assembly
trans-synaptic signaling by trans-synaptic complex
synaptic membrane adhesion
regulation of presynapse assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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