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Invitrogen
RSK2 Recombinant Rabbit Monoclonal Antibody (K01_2P36)
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FIGURE: 1 / 2
RSK2 Antibody (MA564198) in IHC (P)
Immunohistochemistry (Paraffin) analysis of RSK2 in paraffin-embedded Human lung cancer tissue. Samples were incubated with RSK2 recombinant monoclonal (Product # MA564198). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Product Details
MA564198
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Hamster,
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_2P36
Immunogen
A synthetic peptide of human Rsk 2/MAPKAP Kinase 1b.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
50mM tris glycine, pH 7.4, with 40% glycerol, 0.05% BSA, 150mM NaCl
Contains
0.01% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 90 kDa ribosomal protein S6 kinase 3; epididymis secretory sperm binding protein; Insulin-stimulated protein kinase 1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; p90-RSK 3; pp90RSK2; Ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; Ribosomal S6 kinase 2; RPS6KA3; RSK-2; S6K-alpha-3; unnamed protein product
Gene Aliases: CLS; HU-3; ISPK-1; ISPK1; MAPKAPK1B; MRX19; p90-RSK2; pp90RSK2; RPS6KA3; RSK; RSK2; S6K-alpha3; XLID19
UniProt ID: (Human) P51812
Entrez Gene ID: (Human) 6197, (Chinese hamster) 100750954
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
ribosomal protein S6 kinase activity
protein binding
ATP binding
kinase activity
transferase activity
protein kinase binding
metal ion binding
protein serine kinase activity
protein modifying enzyme
skeletal system development
toll-like receptor signaling pathway
signal transduction
chemical synaptic transmission
central nervous system development
positive regulation of cell growth
response to lipopolysaccharide
intracellular signal transduction
TORC1 signaling
negative regulation of apoptotic process
regulation of translation in response to stress
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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