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Invitrogen
XRCC1 Recombinant Rabbit Monoclonal Antibody (K01_2Q02)
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Product Details
MA564239
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
K01_2Q02
Immunogen
A synthetic peptide of human XRCC1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
50mM tris glycine, pH 7.4, with 40% glycerol, 150mM NaCl, 0.05% BSA
Contains
0.01% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA repair protein XRCC1; DNA-repair protein; unnamed protein product; X-ray repair complementing defective repair in Chinese hamster cells 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1
Gene Aliases: RCC; SCAR26; Xrcc-1; XRCC1
UniProt ID: (Human) P18887, (Rat) Q9ESZ0
Entrez Gene ID: (Human) 7515, (Rat) 84495
single strand break repair
DNA repair
base-excision repair
double-strand break repair
double-strand break repair via nonhomologous end joining
cellular response to DNA damage stimulus
negative regulation of protein ADP-ribosylation
hippocampus development
response to hydroperoxide
telomeric DNA-containing double minutes formation
regulation of base-excision repair
negative regulation of protection from non-homologous end joining at telomere
response to hypoxia
response to organic substance
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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