Search
Invitrogen
GluR2 Monoclonal Antibody (C3)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 3
GluR2 Antibody (MA566134) in IHC (P)
Immunohistochemistry analysis of GluR2 in paraffin-embedded Human Cerebellum tissue. Samples were incubated with GluR2 Monoclonal (Product # MA566134) antibody using a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG (2 µg/mL) and DAB.
Product Details
MA566134
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
C3
Immunogen
Recombinant Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (Asn413-Lys527)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AMPA receptor subunit GluA2; AMPA-selective glutamate receptor 2; GluR-2; GluR-B; GluR-K2; GluR2; glutamate receptor; Glutamate receptor 2; Glutamate receptor ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 2; ionotropic glutamate receptor AMPA 2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943; unnamed protein product
Gene Aliases: GluA2; gluR-2; gluR-B; GluR-K2; GLUR2; GLURB; GRIA2; HBGR2; NEDLIB
UniProt ID: (Human) P42262
Entrez Gene ID: (Pig) 100622950, (Human) 2891
beta-amyloid binding
ionotropic glutamate receptor activity
AMPA glutamate receptor activity
ion channel activity
protein binding
ligand-gated ion channel activity
signaling receptor activity
ligand-gated monoatomic cation channel activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
transmembrane signal receptor
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support