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Invitrogen
Collagen III Polyclonal Antibody, Biotin
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FIGURE: 1 / 1
Collagen III Antibody (PA1-28532) in IHC (P)
Immunohistochemistry analysis of Collagen III was performed in human skin and testis tissue using Collagen III Polyclonal Antibody, Biotin (Product # PA1-28532) at a dilution of 1:400 for 45 minutes a room temperature. The antibody showed strong staining in FFPE sections of human skin (left, dermis) with moderate to strong red staining and testis (right) where strong staining was observed within connective ... View More
Product Details
PA1-28532
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Collagen Type III from human and bovine placenta.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 1% BSA
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-28532 detects Collagen III from bovine, human samples.
Target Information
Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-1 type III collagen; alpha-1(III) procollagen; alpha1 (III) collagen; COL 3; COL3; COL3 alpha 1; Collagen 3; Collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant); collagen, type III, alpha 1 chain, fibril forming; Collagen3; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; procollagen, type III, alpha 1; unnamed protein product
Gene Aliases: AW550625; Col3a-1; COL3A1; EDS4A; EDSVASC; mKIAA4231; MMS10-W; Ms10w; PMGEDSV
UniProt ID: (Human) P02461, (Mouse) P08121, (Rat) P13941
Entrez Gene ID: (Human) 1281, (Bovine) 510833, (Mouse) 12825, (Rat) 84032
blood vessel development
in utero embryonic development
neuron migration
tissue homeostasis
chondrocyte differentiation
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
heart development
response to radiation
gene expression
peptide cross-linking
layer formation in cerebral cortex
cerebral cortex development
platelet activation
extracellular matrix organization
collagen fibril organization
lung development
transforming growth factor beta1 production
response to cytokine
positive regulation of Rho protein signal transduction
multicellular organism growth
aorta development
limb joint morphogenesis
wound healing
skin development
fibroblast proliferation
elastic fiber assembly
animal organ development
digestive tract development
system development
negative regulation of immune response
cartilage development
endochondral bone morphogenesis
aorta smooth muscle tissue morphogenesis
cellular response to amino acid stimulus
basement membrane organization
fibril organization
response to angiotensin
negative regulation of neuron migration
extracellular fibril organization
skeletal system development
aging
response to mechanical stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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