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Invitrogen
mGluR6 Polyclonal Antibody
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FIGURE: 1 / 2
mGluR6 Antibody (PA1-46253) in ICC/IF
Immunocytochemistry analysis of mGluR6 in trapezoid body in mouse brain. Samples were incubated in mGluR6 polyclonal antibody (Product # PA1-46253) followed by anti-rabbit Cy3 conjugated secondary antibodies (red). DAPI was used to counterstain cell nuclei.
Product Details
PA1-46253
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C-terminus of rat metabotropic Glutamate Receptor 6 (mGluR6).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody reacts weakly on human brain tissue.
Target Information
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member F; glutamate receptor; Metabotropic glutamate receptor 6; mGluR6
Gene Aliases: BC021919; Gm3; Gprc1f; Grm6; Mglur6; nerg1; nob2; nob3; nob4
UniProt ID: (Rat) P35349, (Mouse) Q5NCH9
Entrez Gene ID: (Rat) 24419, (Mouse) 108072
signal transduction
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
locomotory behavior
detection of light stimulus involved in visual perception
sensory perception of light stimulus
regulation of synaptic transmission, glutamatergic
retina development in camera-type eye
positive regulation of calcium ion import
G-protein coupled receptor signaling pathway
visual perception
response to stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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