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          • Primary Antibodies ›
          • MCF2L Antibodies

          Invitrogen

          MCF2L Polyclonal Antibody

          View all (5) MCF2L antibodies

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          Cite MCF2L Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          MCF2L Antibody in Western Blot (WB)
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          MCF2L Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MCF2L Antibody (PA5-100662) in WB

          Western blot analysis of MCF2L in Molt-4 cell lysate (left lane: treated with the antigen-specific peptide). Samples were incubated with MCF2L polyclonal antibody (Product # PA5-100662). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MCF2L Antibody in Western Blot (WB)
          MCF2L Polyclonal Antibody

          Product Details

          PA5-100662

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human MCF2L(Accession O15068), corresponding to amino acid residues V295-Q345.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2850166

          Product Specific Information

          Antibody detects endogenous levels of total MCF2L.

          Target Information

          This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DBL's big sister; FLJ12122; Guanine nucleotide exchange factor DBS; KIAA0362; mcf.2 transforming sequence-like; MCF2 transforming sequence-like protein; MCF2-transforming sequence-like protein; OST oncogene; RP11-98F14.2; unnamed protein product

          View more View less

          Gene Aliases: ARHGEF14; DBS; KIAA0362; mcf 2l; MCF2L; OST

          View more View less

          UniProt ID: (Human) O15068, (Rat) Q63406

          View more View less

          Entrez Gene ID: (Human) 23263, (Rat) 117020

          View more View less

          Function(s)
          guanyl-nucleotide exchange factor activity protein binding lipid binding phosphatidylinositol binding Rho guanyl-nucleotide exchange factor activity 1-phosphatidylinositol binding guanyl-nucleotide exchange factor
          Process(es)
          positive regulation of Rho protein signal transduction intracellular signal transduction regulation of small GTPase mediated signal transduction Rho protein signal transduction positive regulation of transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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