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Invitrogen
HOXA1 Polyclonal Antibody
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FIGURE: 1 / 8
HOXA1 Antibody (PA5-101116) in IHC (P)
Immunohistochemistry analysis of HOXA1 in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with HOXA1 polyclonal antibody (Product # PA5-101116) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-101116
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human HOXA1(Accession P49639), corresponding to amino acid residues G56-A106.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total HOXA1.
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14 kDa polypeptide encoded by the shortest HOXA1 mRNA; 24 kDa polypeptide encoded by the longest HOXA1 transcript; 36 kDa homeodomain-containing protein encoded by the middle size HOXA1 transcript; early retinoic acid 1; homeo box A1; homeobox 1F; homeobox A1; homeobox protein Hox-1.6; Homeobox protein Hox-1F; Homeobox protein Hox-A1; homeoboxless protein ERA-1-399; homeotic protein ERA-1-993; Hox 1.6-like protein; HOX A1 homeodomain protein; HOXA 1; HOXA-1; HOXA1; lab-like protein; MGC45232; unnamed protein product
Gene Aliases: BSAS; ERA1; Hox-1.6; HOX1; HOX1F; HOXA1
UniProt ID: (Human) P49639
Entrez Gene ID: (Human) 3198, (Mouse) 15394, (Rat) 103690132
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
homeodomain transcription factor
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
sensory perception of sound
optokinetic behavior
anatomical structure morphogenesis
abducens nerve formation
outer ear morphogenesis
positive regulation of transcription from RNA polymerase II promoter
embryonic neurocranium morphogenesis
inner ear development
artery morphogenesis
regulation of behavior
cognition
neuromuscular process
artery development
semicircular canal formation
cochlea development
cochlea morphogenesis
transcription, DNA-templated
multicellular organism development
nervous system development
motor neuron axon guidance
anterior/posterior pattern specification
rhombomere 3 development
rhombomere 4 development
rhombomere 5 development
facial nerve structural organization
facial nucleus development
central nervous system neuron differentiation
hindbrain development
inner ear morphogenesis
anatomical structure formation involved in morphogenesis
cellular response to retinoic acid
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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