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Invitrogen
PP1 beta Polyclonal Antibody
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FIGURE: 1 / 3
PP1 beta Antibody (PA5-102349) in IHC (P)
Immunohistochemistry analysis of PP1 beta in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PP1 beta polyclonal antibody (Product # PA5-102349) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102349
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PPP1CB(Accession P62140), corresponding to amino acid residues S298-R327.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PPP1CB.
Target Information
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein Li 80p; MGC21657; myosin phosphatase; PP-1B; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX; PPP1CB; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase-1a; Serine/threonine-protein phosphatase PP1-beta catalytic subunit; unnamed protein product
Gene Aliases: 1200010B19; HEL-S-80p; MP; NSLH2; PP-1B; PP1B; PP1beta; PP1c; PPP1beta; PPP1CB; PPP1CD
UniProt ID: (Human) P62140, (Mouse) P62141, (Rat) P62142
Entrez Gene ID: (Human) 5500, (Mouse) 19046, (Rat) 25594
MAPK cascade
glycogen metabolic process
protein dephosphorylation
regulation of cell adhesion
circadian regulation of gene expression
regulation of circadian rhythm
entrainment of circadian clock by photoperiod
rhythmic process
cell division
carbohydrate metabolic process
regulation of glycogen biosynthetic process
regulation of glycogen catabolic process
cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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