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Invitrogen
NTS Polyclonal Antibody
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FIGURE: 1 / 3
NTS Antibody (PA5-103974) in IHC (P)
Immunohistochemistry analysis of NTS in rat kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with NTS polyclonal antibody (Product # PA5-103974) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103974
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NTS(Accession P30990), corresponding to amino acid residues G130-Y170.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total NTS.
Target Information
NTS is a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neuromedin N; Neurotensin/neuromedin N; NmN; NTS; pro-neurotensin/neuromedin; unnamed protein product
Gene Aliases: 5033428E16Rik; NMN-125; NN; NT; NT/N; NTS; NTS1
UniProt ID: (Human) P30990, (Mouse) Q9D3P9
Entrez Gene ID: (Human) 4922, (Mouse) 67405, (Rat) 299757
visual learning
regulation of blood vessel size
liver development
response to amphetamine
hyperosmotic response
response to estradiol
response to cocaine
digestive tract development
response to axon injury
response to mineralocorticoid
response to corticosterone
cellular response to lithium ion
cellular response to dexamethasone stimulus
response to antipsychotic drug
cellular response to nerve growth factor stimulus
signal transduction
neuropeptide signaling pathway
positive regulation of gene expression
negative regulation of gene expression
killing of cells of other organism
positive regulation of protein kinase B signaling
antimicrobial humoral immune response mediated by antimicrobial peptide
regulation of blood vessel diameter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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