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          • Primary Antibodies ›
          • SHC3 Antibodies

          Invitrogen

          SHC3 Polyclonal Antibody

          View all (12) SHC3 antibodies

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          Cite SHC3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          SHC3 Antibody in Western Blot (WB)
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          SHC3 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          SHC3 Antibody (PA5-106262) in WB

          Western blot analysis of SHC3 in extracts from H2O2 treated COS-7 cells. Samples were incubated with SHC3 polyclonal antibody (Product # PA5-106262). The lane on the left was treated with blocking peptide. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SHC3 Antibody in Western Blot (WB)
          SHC3 Antibody in Western Blot (WB)
          SHC3 Polyclonal Antibody

          Product Details

          PA5-106262

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Non-human primate, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human SHC3(Accession Q92529), corresponding to amino acid residues L398-K448.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2853943

          Product Specific Information

          Antibody detects endogenous levels of total Shc3.

          Target Information

          Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: N-Shc; Neuronal Shc; Protein Rai; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHC-transforming protein 3; SHC-transforming protein C; Shc3 p51; src homology 2 domain-containing transforming protein C3; Src homology 2 domain-containing-transforming protein C3

          View more View less

          Gene Aliases: N-Shc; NSHC; RAI; SHC3; SHCC

          View more View less

          UniProt ID: (Human) Q92529, (Mouse) Q61120

          View more View less

          Entrez Gene ID: (Human) 53358, (Rat) 114858, (Mouse) 20418

          View more View less

          Function(s)
          phosphotyrosine binding protein binding receptor tyrosine kinase binding receptor binding protein kinase binding scaffold/adaptor protein
          Process(es)
          transmembrane receptor protein tyrosine kinase signaling pathway epidermal growth factor receptor signaling pathway central nervous system development intracellular signal transduction learning or memory synaptic transmission, glutamatergic signal transduction
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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