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Invitrogen
USP33 Polyclonal Antibody
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Product Details
PA5-106447
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human USP33(Accession Q8TEY7), corresponding to amino acid residues M292-D342.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total USP33.
Target Information
DNA-directed RNA polymerase I subunit RPA43 or Twist neighbor protein (Twistnb)belongs to the eukaryotic RPA43 RNA polymerase subunit family. It catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.Twistnb is the component of RNA polymerase I which synthesizes ribosomal RNA precursors. It is widely expressed in all fetal and adult tissues, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. Twist genes are essential for embryonic development and are conserved from jellyfish to human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Deubiquitinating enzyme 33; hVDU1; pVHL-interacting deubiquitinating enzyme 1; Ubiquitin carboxyl-terminal hydrolase 33; ubiquitin specific protease 33; Ubiquitin thioesterase 33; ubiquitin thiolesterase 33; ubiquitin-specific processing protease; Ubiquitin-specific-processing protease 33; unnamed protein product; VHL-interacting deubiquitinating enzyme 1; Vhlh-interacting deubiquitinating enzyme 1
Gene Aliases: 9830169D19Rik; AA409780; KIAA1097; USP33; VDU1
UniProt ID: (Human) Q8TEY7, (Mouse) Q8R5K2
Entrez Gene ID: (Human) 23032, (Mouse) 170822, (Rat) 310960
G-protein coupled receptor binding
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
peptidase activity
cysteine-type peptidase activity
zinc ion binding
hydrolase activity
small GTPase binding
ubiquitin binding
metal ion binding
Ral GTPase binding
thiol-dependent ubiquitinyl hydrolase activity
cysteine protease
proteolysis
ubiquitin-dependent protein catabolic process
endocytosis
nervous system development
axon guidance
regulation of G-protein coupled receptor protein signaling pathway
cell migration
protein deubiquitination
protein stabilization
centrosome duplication
protein K63-linked deubiquitination
protein K48-linked deubiquitination
positive regulation of autophagosome assembly
cellular response to starvation
regulation of autophagy
negative regulation of protein binding
positive regulation of protein binding
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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