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Invitrogen
Phospho-Stathmin 1 (Ser25) Polyclonal Antibody
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FIGURE: 1 / 3
Phospho-Stathmin 1 (Ser25) Antibody (PA5-110161) in IHC (P)
Immunohistochemistry analysis of Phospho-Stathmin 1 (Ser25) in paraffin-embedded human breast carcinoma. Samples were incubated with Phospho-Stathmin 1 (Ser25) Polyclonal antibody (Product # PA5-110161). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
PA5-110161
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphorylated peptide around S25 of human Stathmin 1 (NP_0055541)
Conjugate
Form
Liquid
Concentration
1.12 mg/mL
Amount
112 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ILSPRS
Target Information
Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; Leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; Stathmin; stathmin 1 variant; stathmin 1/oncoprotein 18; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215; unnamed protein product
Gene Aliases: 19k; C1orf215; Lag; LAP18; OP18; P18; P19; Pig; PP17; Pp18; PP19; PR22; prosolin; SMN; STMN1
UniProt ID: (Human) P16949, (Rat) P13668, (Mouse) P54227
Entrez Gene ID: (Human) 3925, (Rat) 29332, (Mouse) 16765
microtubule depolymerization
mitotic spindle organization
axonogenesis
brain development
response to virus
regulation of microtubule polymerization or depolymerization
negative regulation of microtubule polymerization
neuron projection development
intracellular signal transduction
positive regulation of cellular component movement
regulation of cytoskeleton organization
mitotic cytokinesis
signal transduction
nervous system development
cell differentiation
regulation of cell migration
negative regulation of Rho protein signal transduction
hepatocyte growth factor receptor signaling pathway
negative regulation of stress fiber assembly
establishment of skin barrier
negative regulation of thrombin receptor signaling pathway
negative regulation of guanyl-nucleotide exchange factor activity
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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