Search

  • Contact Us
  • Quick Order

Invitrogen

NGAL Polyclonal Antibody

View all (119) NGAL antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
NGAL Polyclonal Antibody

Product Details

PA5-115503

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human LCN2(Accession P80188), corresponding to amino acid residues Q40-L90.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2900139

Product Specific Information

Antibody detects endogenous levels of total LCN2.

Target Information

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; HGNC:6526; LCN2; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin-2; Lipocalin2; migration-stimulating factor inhibitor; Neutrophil gelatinase-associated lipocalin; neutrophil lipocalin; NGAL; Oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; SV-40-induced 24P3 protein; unnamed protein product; uterocalin

View more View less

Gene Aliases: 24p3; AW212229; HNL; LCN2; MSFI; NGAL; p25; Sip24

View more View less

UniProt ID: (Human) P80188, (Mouse) P11672, (Rat) P30152

View more View less

Entrez Gene ID: (Human) 3934, (Mouse) 16819, (Rat) 170496

View more View less

Function(s)
protease binding iron ion binding protein binding small molecule binding identical protein binding iron ion sequestering activity enterobactin binding transporter activity protein homodimerization activity transfer/carrier protein
Process(es)
immune system process ion transport iron ion transport apoptotic process acute-phase response response to oxidative stress short-term memory long-term memory response to xenobiotic stimulus response to virus response to bacterium response to herbicide response to toxic substance response to blue light response to fructose response to iron(II) ion response to mycotoxin positive regulation of endothelial cell migration positive regulation of gene expression siderophore transport positive regulation of cell projection organization response to nutrient levels cellular response to nutrient levels response to lipopolysaccharide cellular response to increased oxygen levels defense response to bacterium positive regulation of apoptotic process positive regulation of neuron apoptotic process innate immune response cellular response to hydrogen peroxide cellular response to lipopolysaccharide cellular response to interleukin-1 cellular response to interleukin-6 cellular response to tumor necrosis factor cellular response to hypoxia cellular response to X-ray extrinsic apoptotic signaling pathway in absence of ligand positive regulation of hippocampal neuron apoptotic process negative regulation of hippocampal neuron apoptotic process positive regulation of cold-induced thermogenesis positive regulation of reactive oxygen species biosynthetic process response to kainic acid positive regulation of iron ion import across plasma membrane cellular response to beta-amyloid positive regulation of endothelial tube morphogenesis cellular response to nerve growth factor stimulus positive regulation of reactive oxygen species metabolic process transport response to drug iron ion homeostasis protein homotrimerization
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support