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Invitrogen
GNMT Polyclonal Antibody
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FIGURE: 1 / 1
GNMT Antibody (PA5-117061) in WB
Western blot analysis of GNMT in extracts of various cell lines. Samples were incubated with GNMT Polyclonal antibody (Product # PA5-117061) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-117061
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human GNMT (NP_0618331)
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Amount
90 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: Mouse liver, Mouse kidney, Mouse pancreas, Rat liver, Rat kidney
Immunogen sequence: MVDSVYRTRS LGVAAEGLPD QYADGEAARV WQLYIGDTRS RTAEYKAWLL GLLRQHGCQR VLDVACGTGV DSIMLVEEGF SVTSVDASDK MLKYALKERW NRRHEPAFDK WVIEEANWMT LDKDVPQSAE GGFDAVICLG NSFAHLPDCK GDQSEHRLAL KNIASMVRAG GLLVIDHRNY DHILSTGCAP PGKNIYYKSD LTKDVTTSVL IVNNKAHMVT LDYTVQVPGA GQDGSPGLSK FRLSYYPHCL ASFTELLQAA FGGKCQHSVL GDFKPYKPGQ TYIPCYFIHV LKRTD
Target Information
The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2.1.1.20; Folate-binding protein; glycine methyltransferase; glycine N methyl transferase; Glycine N-methyltransferase
Gene Aliases: Fbp-cII; Gnmt
UniProt ID: (Mouse) Q9QXF8, (Rat) P13255
Entrez Gene ID: (Mouse) 14711, (Rat) 25134
glycogen metabolic process
regulation of gluconeogenesis
methionine metabolic process
one-carbon metabolic process
methylation
S-adenosylmethionine metabolic process
protein homotetramerization
glycine metabolic process
S-adenosylhomocysteine metabolic process
folic acid metabolic process
protein tetramerization
sarcosine metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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