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Invitrogen
Cathepsin V Polyclonal Antibody
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FIGURE: 1 / 1
Cathepsin V Antibody (PA5-117101) in WB
Western blot analysis of Cathepsin V in extracts of various cell lines. Samples were incubated with Cathepsin V Polyclonal antibody (Product # PA5-117101) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-117101
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 105-334 of human CTSV (NP_0013242)
Conjugate
Form
Liquid
Concentration
2.46 mg/mL
Amount
246 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HeLa, A-549, Mouse liver, Rat liver
Immunogen sequence: VFREPLFLDL PKSVDWRKKG YVTPVKNQKQ CGSCWAFSAT GALEGQMFRK TGKLVSLSEQ NLVDCSRPQG NQGCNGGFMA RAFQYVKENG GLDSEESYPY VAVDEICKYR PENSVANDTG FTVVAPGKEK ALMKAVATVG PISVAMDAGH SSFQFYKSGI YFEPDCSSKN LDHGVLVVGY GFEGANSNNS KYWLVKNSWG PEWGSNGYVK IAKDKNNHCG IATAASYPNV
Target Information
Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cathepsin L2; cathepsin L2, preproprotein; Cathepsin U; Cathepsin V; cysteine protease; PRO305; unnamed protein product; UNQ268
Gene Aliases: CATL2; CTSL2; CTSU; CTSV; UNQ268/PRO305
UniProt ID: (Human) O60911
Entrez Gene ID: (Human) 1515
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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