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Invitrogen
RC74 Polyclonal Antibody
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Product Details
PA5-117481
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Integrator complex subunit 9 protein (368-658aa)
Conjugate
Form
Liquid
Concentration
5 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
INTS9 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A)and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1)and U2 (RNU2)(Baillat et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Int9; Integrator complex subunit 9; Protein related to CPSF subunits of 74 kDa; RC-74; unnamed protein product
Gene Aliases: CPSF2L; INT9; INTS9; RC74
UniProt ID: (Human) Q9NV88
Entrez Gene ID: (Human) 55756
snRNA processing
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of transcription elongation from RNA polymerase II promoter
snRNA 3'-end processing
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
regulation of cellular response to growth factor stimulus
RNA polymerase II transcription initiation surveillance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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