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          • Primary Antibodies ›
          • hnRNP C Antibodies

          Invitrogen

          hnRNP C Polyclonal Antibody

          View all (12) hnRNP C antibodies

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          Cite hnRNP C Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (10)
          hnRNP C Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          hnRNP C Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          hnRNP C Antibody (PA5-117991) in ICC/IF

          Immunocytochemistry analysis of hnRNP C in HEK293 cells. Samples were treated with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, incubated with polyclonal antibody (Product # PA5-117991) with a dilution of 1:200 (4°C overnight), followed by Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and DAPI (blue). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          hnRNP C Antibody in Immunocytochemistry (ICC/IF)
          hnRNP C Antibody in Immunocytochemistry (ICC/IF)
          hnRNP C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          hnRNP C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          hnRNP C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          hnRNP C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          hnRNP C Antibody in Western Blot (WB)
          hnRNP C Antibody in Western Blot (WB)
          hnRNP C Antibody in Immunoprecipitation (IP)
          hnRNP C Antibody in Immunoprecipitation (IP)

          Product Details

          PA5-117991

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          Immunoprecipitation (IP)

          5-10 µL/mg of lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          E. coli-derived Human HNRNPC fragment

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Antigen affinity chromatography, Protein A

          Storage buffer

          PBS, pH 7

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2902596

          Target Information

          This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: C protein; heterogeneous nuclear ribonucleoprotein C (C1/C2); Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; hnRNP C2 protein; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; unnamed protein product

          View more View less

          Gene Aliases: C1; C2; HNRNP; HNRNPC; HNRPC; MRD74; SNRPC

          View more View less

          UniProt ID: (Human) P07910

          View more View less

          Entrez Gene ID: (Human) 3183

          View more View less

          Function(s)
          nucleic acid binding RNA binding mRNA 3'-UTR binding protein binding poly(U) RNA binding nucleosomal DNA binding identical protein binding telomerase RNA binding N6-methyladenosine-containing RNA binding
          Process(es)
          mRNA splicing, via spliceosome osteoblast differentiation chromatin remodeling mRNA processing RNA splicing negative regulation of telomere maintenance via telomerase 3'-UTR-mediated mRNA stabilization
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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