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Invitrogen
TDH Polyclonal Antibody
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FIGURE: 1 / 6
TDH Antibody (PA5-119260) in IHC (P)
Immunohistochemistry analysis of L-Threonine Dehydrogenase in paraffin-embedded Human Cerebrum tissue. Samples were incubated with polyclonal antibody (Product # PA5-119260) at a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
Product Details
PA5-119260
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein L-Threonine Dehydrogenase. The antigen corresponds to amino acid range 1-229 of the target protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene appears to be an evolving pseudogene of L-threonine 3-dehydrogenase (TDH). In both prokaryotes and eukaryotes, TDH catalyzes the first of two steps in one of two L-threonine degradation pathways. However, in human, the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein; the predicted protein lacks most of the C-terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins. This suggests that the human gene is therefore a pseudogene. Transcripts of this gene are found in all tissues and alternatively spliced transcripts have been described. It is not known if these transcripts are translated, or if the possible protein product provides any functional role.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: L-threonine 3-dehydrogenase; L-threonine 3-dehydrogenase, mitochondrial; L-Threonine Dehydrogenase; TDH; unnamed protein product
Gene Aliases: SDR14E1P; TDH
UniProt ID: (Pig) Q8MIR0
Entrez Gene ID: (Pig) 397065, (Human) 157739
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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