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Invitrogen
TIF1 gamma Polyclonal Antibody
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FIGURE: 1 / 4
TIF1 gamma Antibody (PA5-119959) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human placenta tissue using TIF1 gamma Polyclonal Antibody (Product # PA5-119959). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 1% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the TIF1 gamma antibody at a... View More
Product Details
PA5-119959
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within human TIF1 gamma aa 900-1127.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: K562 cell lysates, mouse uterus tissue lysates, human placenta tissue, human thyroid tissue.
Subcellular Location: Nucleus.
Target Information
TIF1 gamma is a member of the Transcriptional Intermediary Factor 1 family, which serve as coactivators and corepressors. Its structure is similar to TIF1 alpha and TIF1 beta, exhibiting multiple domains (RING finger, coiled coil, B boxes, PHD/TTC, and bromodomain). TIF1 gamma functions in cell differentiation and development, playing a role in differentiation of hematopoietic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM33; Ectodermin homolog; Protein Rfg7; RET-fused gene 7 protein; RING-type E3 ubiquitin transferase TRIM33; TIF 1-g; TIF1-gamma; Transcription intermediary factor 1-gamma; transcriptional intermediary factor 1 gamma; Tripartite motif-containing protein 33; unnamed protein product
Gene Aliases: 8030451N04Rik; AI413936; ECTO; KIAA1113; PTC7; RFG7; TF1G; TIF1G; TIF1GAMMA; TIFGAMMA; TRIM33
UniProt ID: (Human) Q9UPN9, (Mouse) Q99PP7
Entrez Gene ID: (Human) 51592, (Mouse) 94093
DNA binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
transferase activity
metal ion binding
ubiquitin protein ligase activity
co-SMAD binding
R-SMAD binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
chromatin/chromatin-binding, or -regulatory protein
negative regulation of transcription from RNA polymerase II promoter
protein ubiquitination
regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
negative regulation of transcription, DNA-templated
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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