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Invitrogen
RRAGA Polyclonal Antibody
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FIGURE: 1 / 2
RRAGA Antibody (PA5-120332) in IHC (P)
Immunohistochemistry analysis of RRAGA in paraffin-embedded human placenta. Samples were incubated with RRAGA Polyclonal antibody (Product # PA5-120332) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
PA5-120332
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 213-313 of human RRAGA (NP_0065611)
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Amount
101 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: 293T, Mouse brain, Rat brain, Rat kidney. The target is usually found in the following locations: Cytoplasm, Lysosome, Nucleus.
Immunogen sequence: VISHYQCKEQ RDVHRFEKIS NIIKQFKLSC SKLAASFQSM EVRNSNFAAF IDIFTSNTYV MVVMSDPSIP SAATLINIRN ARKHFEKLER VDGPKHSLLM R
Target Information
RRAGA (Ras Related GTP Binding A) is a Protein Coding gene. Diseases associated with RRAGA include Familial Renal Oncocytoma and Tuberous Sclerosis 1. Among its related pathways are mTOR signalling and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and GTP binding. An important paralog of this gene is RRAGB.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenovirus E3 14.7 kDa-interacting protein 1; adenovirus E3-14.7K interacting protein 1; FIP-1; Rag A; Ras-related GTP-binding protein A; Ras-related GTP-binding protein ragA; rraga; rraga {ECO:0000312|RGD:619804}; unnamed protein product
Gene Aliases: 1300010C19Rik; AI255374; FIP-1; FIP1; RAGA; RRAGA
UniProt ID: (Human) Q7L523, (Rat) Q63486, (Mouse) Q80X95
Entrez Gene ID: (Human) 10670, (Rat) 117044, (Mouse) 68441
autophagosome assembly
cytoplasmic translation
apoptotic process
protein localization
cellular response to starvation
negative regulation of autophagy
cellular response to nutrient levels
positive regulation of TOR signaling
tumor necrosis factor-mediated signaling pathway
cellular response to amino acid starvation
intracellular signal transduction
TORC1 signaling
glucose homeostasis
negative regulation of translational initiation
positive regulation of translational initiation
cellular response to methionine
protein localization to lysosome
cellular response to amino acid stimulus
protein localization to membrane
positive regulation of TORC1 signaling
biological_process
metabolic process
cell death
regulation of autophagy
modulation by virus of host morphology or physiology
cellular protein localization
positive regulation of cytolysis
regulation of cytolysis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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