Search
Invitrogen
ELF5 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-121071
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human ELF5 (NP_938195.1).
Conjugate
Form
Liquid
Concentration
0.75 mg/mL
Amount
75 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: Rat lung, Rat kidney. The target is usually found in the following locations: Nucleus.
Immunogen sequence: EEYYPAFEHQ TACDSYWTSV HPEYWTKRHV WEWLQFCCDQ YKLDTNCISF CNFNISGLQL CSMTQEEFVE AAGLCGEYLY FILQNIRTQG YSFFNDAEES KATIKDYADS N
Target Information
ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: E74-like factor 5; E74-like factor 5 (ets domain transcription factor); elf-5; Epithelium specific Ets-2; Epithelium-restricted ESE-1-related Ets factor; Epithelium-specific Ets transcription factor 2; ESE-2; Ets transcription factor; ETS-related transcription factor Elf-5; unnamed protein product
Gene Aliases: ELF5; ESE-2; ESE-5; ESE-5.; ESE2
UniProt ID: (Human) Q9UKW6, (Mouse) Q8VDK3
Entrez Gene ID: (Human) 2001, (Mouse) 13711, (Rat) 366142
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
winged helix/forkhead transcription factor
ectodermal cell fate commitment
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
ectoderm development
cell differentiation
somatic stem cell population maintenance
positive regulation of transcription from RNA polymerase II promoter
mammary gland epithelial cell differentiation
trophoblast giant cell differentiation
negative regulation of cell differentiation involved in embryonic placenta development
transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support