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Invitrogen
SULT1A1 Polyclonal Antibody
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FIGURE: 1 / 2
SULT1A1 Antibody (PA5-12247) in WB
Western blot analysis of SULT1A1 in 293 cell lysates. Samples were incubated with SULT1A1 polyclonal antibody (Product # PA5-12247). Lysates: 2 µg/lane. 293 cell lysates either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SULT1A1 gene.
Product Details
PA5-12247
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 128-160 amino acids from the central region of human SULT1A1
Conjugate
Form
Liquid
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aryl sulfotransferase; Aryl sulfotransferase 1; arylsulfotransferase ST1A4; CSPS; HAST1/HAST2; MGC131921; MGC5163; mSTp1; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; P-PST 1; phenol sulfotransferase; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; phenol/aryl sulfotransferase; ST1A1; ST1A3; ST1A4; sulfokinase; Sulfotransferase 1A1; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulfotransferase, phenol preferring 1; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; Ts-PST
Gene Aliases: AI266890; HAST1/HAST2; OK/SW-cl.88; P-PST; P-PST 1; PST; ST1A1; ST1A3; STP; STP1; SULT1A1; ts-PST; TSPST1
UniProt ID: (Human) P50225
Entrez Gene ID: (Human) 6817, (Mouse) 20887
aryl sulfotransferase activity
protein binding
sulfotransferase activity
transferase activity
flavonol 3-sulfotransferase activity
steroid sulfotransferase activity
3'-phosphoadenosine 5'-phosphosulfate binding
nucleotide binding
N-acetylglucosamine 6-O-sulfotransferase activity
N-acetylgalactosamine 4-O-sulfotransferase activity
heparan sulfate 2-O-sulfotransferase activity
HNK-1 sulfotransferase activity
tyrosine-ester sulfotransferase activity
heparan sulfate 6-O-sulfotransferase activity
trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity
1-phenanthrol sulfotransferase activity
3-phenanthrol sulfotransferase activity
4-phenanthrol sulfotransferase activity
trans-3,4-dihydrodiolphenanthrene sulfotransferase activity
9-phenanthrol sulfotransferase activity
2-phenanthrol sulfotransferase activity
phenanthrol sulfotransferase activity
1-hydroxypyrene sulfotransferase activity
protein homodimerization activity
galactose 3-O-sulfotransferase activity
proteoglycan sulfotransferase activity
cholesterol sulfotransferase activity
hydroxyjasmonate sulfotransferase activity
transferase
ethanol catabolic process
catecholamine metabolic process
lipid metabolic process
xenobiotic metabolic process
steroid metabolic process
estrogen metabolic process
amine metabolic process
flavonoid metabolic process
thyroid hormone metabolic process
dopamine catabolic process
3'-phosphoadenosine 5'-phosphosulfate metabolic process
sulfation
drug metabolic process
4-nitrophenol metabolic process
response to glucocorticoid
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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