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Invitrogen
Connexin 26 Polyclonal Antibody
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FIGURE: 1 / 5
Connexin 26 Antibody (PA5-141111) in IHC (P)
Immunohistochemistry analysis of Connexin-26 in paraffin-embedded human liver tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with Connexin-26 Polyclonal antibody (Product # PA5-141111) using a dilution of 1:200 for 30 ... View More
Product Details
PA5-141111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within rat Connexin-26 aa 90-130.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variables (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: connexin 26; Connexin-26; connexin26; transmembrane protein; mutant CX26 protein; Cx26; gap junction beta 2 proteinc; Gap junction beta-2 protein; gap junction channel protein connexin 26; gap junction membrane channel protein beta 2; gap junction protein; gap junction protein, beta 2, 26kDa; mutant connexin 26; transmembrane protein; mutant gap junction beta 2 protein; mutant gap junction protein beta 2; unnamed protein product
Gene Aliases: AI325222; BAPS; Cnx26; CX26; CXN-26; DFNA3; DFNA3A; DFNB1; DFNB1A; Gjb-2; GJB2; HID; KID; NSRD1; PPK
UniProt ID: (Human) P29033, (Mouse) Q00977, (Rat) P21994
Entrez Gene ID: (Human) 2706, (Mouse) 14619, (Rat) 394266
cell communication
cell-cell signaling
sensory perception of sound
cell communication by electrical coupling
gap junction assembly
transmembrane transport
gap junction-mediated intercellular transport
female pregnancy
male genitalia development
response to estradiol
response to progesterone
cellular response to oxidative stress
response to human chorionic gonadotropin
decidualization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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