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Invitrogen
Calbindin D28K Polyclonal Antibody
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FIGURE: 1 / 3
Calbindin D28K Antibody (PA5-143561) in IHC (P)
Chromogenic immunohistochemistry of Calbindin D28K in formalin fixed paraffin embedded rat cerebellum section. Samples were stained with Calbindin D28K polyclonal antibody (Product # PA5-143561) using a dilution of 1:10,000. Detected in DAB (brown) following the ABC method. Hematoxylin (blue) was used as the counterstain. Purkinje cells and their dendrites stain prominently with this antibody.
Product Details
PA5-143561
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Full-length recombinant human protein expressed in and purified from E. coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin 27; Calbindin D28; calbindin-28K; calbindin-D (28k); calbindin-D28k; CalbindinD28K; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; retrovirus-like H primer binding sequence protein; RTVL-H protein; Spot 35 protein; unnamed protein product; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: Brain-2; CAB27; CaBP28K; CALB; Calb-1; CALB1; CB; D-28K
UniProt ID: (Bovine) P04467, (Human) P05937, (Rat) P07171, (Mouse) P12658
Entrez Gene ID: (Bovine) 539930, (Human) 793, (Rat) 83839, (Mouse) 12307
short-term memory
long-term memory
locomotory behavior
retina layer formation
metanephric part of ureteric bud development
cellular response to organic substance
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
regulation of postsynaptic cytosolic calcium ion concentration
learning or memory
response to auditory stimulus
regulation of synaptic plasticity
calcium ion homeostasis
retina development in camera-type eye
cochlea development
regulation of presynaptic cytosolic calcium ion concentration
vitamin D metabolic process
regulation of cytosolic calcium ion concentration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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