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Invitrogen
TM7SF3 Polyclonal Antibody
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FIGURE: 1 / 2
TM7SF3 Antibody (PA5-144053) in WB
Western blot analysis of TM7SF3 using TM7SF3 antibody (Product # PA5-144053). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human RT4 whole cell lysates; Lane 2: human Jurkat whole cell lysates; Lane 3: human MOLT-4 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat mi... View More
Product Details
PA5-144053
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human TM7SF3 recombinant protein (Position: R102-R544).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human RT4 whole cell, human Jurkat whole cell, human MOLT-4 whole cell. Flow: SiHa cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The TM7SF3 gene encodes transmembrane 7 superfamily member 3, a protein that is involved in cellular homeostasis and stress responses. TM7SF3 is characterized by its seven transmembrane domains, which contribute to its role in signal transduction across the cell membrane. This gene is expressed in various tissues and has been implicated in regulating cellular growth and survival pathways, proving critical in the context of cellular response to endoplasmic reticulum (ER) stress and maintaining cellular integrity. TM7SF3 modulates processes such as apoptosis and autophagy, particularly under stress conditions, thus influencing both normal physiological processes and pathological states like cancer. Research has shown that TM7SF3 expression can be altered in certain diseases, affecting pathways that govern cell cycle progression and stress adaptation. Understanding the role of TM7SF3 in cellular signaling and stress management can aid in identifying therapeutic targets for conditions characterized by dysfunctional cellular responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Seven span transmembrane protein; seven transmembrane protein TM7SF3; Transmembrane 7 superfamily member 3; unnamed protein product
Gene Aliases: TM7SF3
UniProt ID: (Human) Q9NS93
Entrez Gene ID: (Human) 51768
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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