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Invitrogen
Myeloperoxidase Polyclonal Antibody
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.jpg?time=20240507?time=20240507 "Myeloperoxidase Antibody (PA5-16672) in IHC")
Product Details
PA5-16672
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Ferret,
Hamster,
Human,
Mouse,
Non-human primate,
Rat,
Rhesus monkey
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Purified human granulocytic MPO
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Purification
purified
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA5-16672 targets Myeloperoxidase in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-16672 immunogen is purified human granulocytic MPO.
PA5-16672 detects MPO-DNA complexes in purified PMA-induced human neutrophil extracellular traps in ELISA application.
Concentration is not determined for this particular antibody. The final product is manufactured from stock material based upon a dilution ratio. The antibody is still quality tested to ensure expected performance and lot-to-lot consistency.
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MPO; Myeloperoxidase; unnamed protein product
Gene Aliases: mKIAA4033; MPO
UniProt ID: (Human) P05164, (Mouse) P11247
Entrez Gene ID: (Human) 4353, (Rat) 303413, (Mouse) 17523
response to yeast
hypochlorous acid biosynthetic process
respiratory burst involved in defense response
defense response
response to oxidative stress
response to mechanical stimulus
removal of superoxide radicals
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
defense response to bacterium
hydrogen peroxide catabolic process
negative regulation of apoptotic process
defense response to fungus
response to gold nanoparticle
aging
negative regulation of growth of symbiont in host
defense response to Gram-positive bacterium
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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