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Invitrogen
JunB Polyclonal Antibody
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Product Details
PA5-17266
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues surrounding Pro169 of human JunB
Conjugate
Form
Liquid
Concentration
82 µg/mL
Amount
8.2 µg
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activator protein 1; Jun B; jun B proto-oncogene; Jun-B oncogene; MyD21; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; transcription factor jun-B; Transcription factor JunB; unnamed protein product
Gene Aliases: AP-1; Jun-b; JUNB
UniProt ID: (Human) P17275, (Mouse) P09450
Entrez Gene ID: (Human) 3726, (Mouse) 16477
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription coactivator activity
transcription factor binding
sequence-specific DNA binding
basic leucine zipper transcription factor
vasculogenesis
osteoblast differentiation
in utero embryonic development
trophectodermal cell differentiation
osteoclast proliferation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
osteoclast differentiation
osteoblast proliferation
regulation of cell proliferation
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
decidualization
response to steroid hormone
regulation of cell cycle
embryonic process involved in female pregnancy
labyrinthine layer blood vessel development
cellular response to calcium ion
integrated stress response signaling
regulation of T-helper 17 cell differentiation
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
transcription from RNA polymerase II promoter
response to radiation
response to mechanical stimulus
cellular process
regulation of cell death
response to lipopolysaccharide
cellular response to hormone stimulus
response to cytokine
response to drug
response to cAMP
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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