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Invitrogen
IRF6 Polyclonal Antibody
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Product Details
PA5-18033
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (TPSMQLPPALPPQ) corresponding to the C-terminus amino acids of IRF6 (aa 455-467).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Interferon regulatory factor 6; IRF-6; transcription factor; unnamed protein product
Gene Aliases: IRF6; LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
UniProt ID: (Human) O14896
Entrez Gene ID: (Human) 3664
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
immune system process
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell proliferation
negative regulation of cell proliferation
negative regulation of keratinocyte proliferation
cell differentiation
keratinocyte differentiation
skin development
keratinocyte proliferation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell development
palate development
limb development
mammary gland epithelial cell differentiation
stem cell proliferation
cranial skeletal system development
negative regulation of stem cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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