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Invitrogen
Nudel Polyclonal Antibody
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Product Details
PA5-19996
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A peptide corresponding to 15 amino acids near the amino terminus of human Nudel.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is Jurkat cell lysate.
PA5-19996 can be used with blocking peptide PEP-0118.
Target Information
This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp451M0318; endooligopeptidase A; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudE-L; nuclear disribution gene E like; Nuclear distribution protein nudE-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog-like 1; NUDE-like protein; Protein mNudE-like; Protein Nudel; unnamed protein product
Gene Aliases: 2600006O07Rik; EOPA; MITAP1; mNudel; NDE1L1; NDE2; NDEL1; NUDEL
UniProt ID: (Human) Q9GZM8, (Mouse) Q9ERR1
Entrez Gene ID: (Human) 81565, (Mouse) 83431
establishment of mitotic spindle orientation
microtubule cytoskeleton organization
neuron migration
inner cell mass cell proliferation
microtubule nucleation
chromosome segregation
mitotic centrosome separation
nervous system development
retrograde axonal transport
insulin receptor signaling pathway
regulation of neuron projection development
cell migration
cerebral cortex radially oriented cell migration
central nervous system neuron axonogenesis
cell differentiation
lysosome localization
regulation of intracellular protein transport
positive regulation of GTPase activity
vesicle transport along microtubule
establishment of chromosome localization
centrosome localization
neurofilament cytoskeleton organization
radial glia-guided pyramidal neuron migration
positive regulation of ruffle assembly
neuron projection extension
proteolysis
transport
multicellular organism development
neuron projection development
positive regulation of axon extension
positive regulation of axon regeneration
nuclear envelope disassembly
canonical Wnt signaling pathway
activation of GTPase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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