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Invitrogen
ApoA1 Polyclonal Antibody
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Product Details
PA5-21166
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human
Published species
Chicken,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid peptide near the carboxy terminus of human ApoA1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
A suggested positive control is chicken liver lysate.
PA5-21166 can be used with blocking peptide PEP-1280.
Target Information
Apolipoprotein A-1 (apo A-1) in human plasma is a major protein component of high density lipoprotein (HDL). The molecular mass is 24 kDa. Apo A-1 is a cofactor for enzymes involved in the normal turnover of cholesterol and is produced in the liver. Plasma concentration is 270-380 mg/100 mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 1-Sep; 2-Sep; Apo a; apo A-1; APO A1; APO I; Apo-AI; apoA-I; ApoAI; Apolipoprotein; Apolipoprotein A-I; apolipoprotein A-I precursor; Apolipoprotein A1; Apolipoprotein AI; epididymis secretory sperm binding protein; MGC102525; MGC117399; MGC124929; prepro-apolipoprotein-AI; proapo-A-I protein; proapolipoprotein; Udpgt; Ugt1; Ugt1a7; unnamed protein product
Gene Aliases: AMYLD3; apo(a); APOA1; HPALP2
UniProt ID: (Chicken) P08250, (Human) P02647
Entrez Gene ID: (Chicken) 396536, (Human) 335
beta-amyloid binding
protein binding
phospholipid binding
high-density lipoprotein particle binding
cholesterol binding
enzyme binding
heat shock protein binding
phosphatidylcholine binding
apolipoprotein A-I receptor binding
identical protein binding
chemorepellent activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding
intermembrane cholesterol transfer activity
receptor binding
lipid transporter activity
lipid binding
apolipoprotein receptor binding
protein homodimerization activity
receptor agonist activity
lipoprotein particle binding
apolipoprotein
regulation of protein phosphorylation
endothelial cell proliferation
phosphatidylcholine biosynthetic process
cholesterol biosynthetic process
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
glucocorticoid metabolic process
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of cholesterol esterification
positive regulation of cholesterol efflux
positive regulation of triglyceride catabolic process
negative regulation of very-low-density lipoprotein particle remodeling
protein oxidation
peptidyl-methionine modification
lipid storage
regulation of intestinal cholesterol absorption
adrenal gland development
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
negative regulation of heterotypic cell-cell adhesion
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
positive regulation of Rho protein signal transduction
lipoprotein metabolic process
lipoprotein biosynthetic process
cholesterol homeostasis
blood vessel endothelial cell migration
reverse cholesterol transport
myoblast differentiation
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
positive regulation of lipid biosynthetic process
negative regulation of inflammatory response
positive regulation of phagocytosis
protein stabilization
negative chemotaxis
positive regulation of lipoprotein lipase activity
vitamin transport
negative regulation of hydrolase activity
positive regulation of stress fiber assembly
regulation of cell cycle
phospholipid homeostasis
negative regulation of cell adhesion molecule production
triglyceride homeostasis
cholesterol import
intermembrane lipid transfer
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of lung ciliated cell differentiation
positive regulation of phospholipid efflux
negative regulation of cytokine production involved in immune response
lipid metabolic process
phospholipid metabolic process
lipid transport
transforming growth factor beta receptor signaling pathway
steroid metabolic process
cholesterol metabolic process
cholesterol transport
negative regulation of interleukin-1 beta production
beta-amyloid formation
high-density lipoprotein particle clearance
acylglycerol homeostasis
negative regulation of response to cytokine stimulus
ERK1 and ERK2 cascade
cellular response to lipoprotein particle stimulus
positive regulation of cholesterol metabolic process
cellular response to beta-amyloid
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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