Search
Invitrogen
MDH2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-21700
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human MDH2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Amount
16 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, mouse brain, rat lung.
Predicted reactivity: Mouse (97%), Rat (96%), Zebrafish (90%), Xenopus laevis (91%), Cat (95%), Pig (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: malate dehydrogenase 2, NAD (mitochondrial); Malate dehydrogenase, mitochondrial; MDH2; mitochondrial malate dehydrogenase 2, NAD; similar to Mus musculus and Sus scrofa MDH; testicular tissue protein Li 120; unnamed protein product
Gene Aliases: DEE51; EIEE51; M-MDH; MDH; Mdh-2; MDH2; MGC:3559; Mor-1; MOR1
UniProt ID: (Human) P40926, (Rat) P04636, (Mouse) P08249
Entrez Gene ID: (Human) 4191, (Rat) 81829, (Mouse) 17448
RNA binding
catalytic activity
oxidoreductase activity
malate dehydrogenase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
L-malate dehydrogenase activity
identical protein binding
malate dehydrogenase (NADP+) activity
protein binding
protein self-association
poly(A) RNA binding
dehydrogenase
gluconeogenesis
tricarboxylic acid cycle
malate metabolic process
aerobic respiration
NAD metabolic process
carboxylic acid metabolic process
malate-aspartate shuttle
oxaloacetate metabolic process
internal protein amino acid acetylation
NADH metabolic process
cellular carbohydrate metabolic process
carbohydrate metabolic process
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support