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Invitrogen
WNT11 Polyclonal Antibody
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FIGURE: 1 / 13
WNT11 Antibody (PA5-21712) in ICC/IF
WNT11 Polyclonal Antibody detects WNT11 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: WNT11 protein stained by WNT11 Polyclonal Antibody (Product # PA5-21712) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
Product Details
PA5-21712
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human WNT11. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.07 mg/mL
Amount
107 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, mouse heart.
Predicted reactivity: Mouse (96%), Rat (96%), Xenopus laevis (81%), Rabbit (97%), Chicken (85%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein Wnt-11; unnamed protein product; wingless-related MMTV integration site 11; wingless-type MMTV integration site family, member 11; WNT11
Gene Aliases: HWNT11; Wnt-11; WNT11
UniProt ID: (Human) O96014, (Mouse) P48615
Entrez Gene ID: (Human) 7481, (Rat) 140584, (Mouse) 22411
osteoblast differentiation
kidney development
epithelial to mesenchymal transition
primary heart field specification
secondary heart field specification
outflow tract morphogenesis
ventricular septum development
atrial septum development
apoptotic process
signal transduction
Wnt signaling pathway, calcium modulating pathway
mesenchymal cell proliferation
Wnt signaling pathway
cell differentiation
neuron differentiation
bone mineralization
adrenal gland development
response to nutrient levels
positive regulation of transforming growth factor beta2 production
intracellular signal transduction
non-canonical Wnt signaling pathway
positive regulation of apoptotic process
cell fate commitment
maintenance of epithelial cell apical/basal polarity
positive regulation of transcription, DNA-templated
paraxial mesoderm formation
notochord morphogenesis
embryonic skeletal system development
artery morphogenesis
palate development
convergent extension involved in axis elongation
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
cloacal septation
ventricular septum morphogenesis
lung-associated mesenchyme development
ureteric bud morphogenesis
negative regulation of cartilage development
somite development
neuroendocrine cell differentiation
secondary palate development
bicellular tight junction assembly
cellular response to mechanical stimulus
cellular response to retinoic acid
stem cell proliferation
mesonephric duct development
negative regulation of mesenchymal cell proliferation
negative regulation of canonical Wnt signaling pathway
negative regulation of fibroblast growth factor production
epithelial cell apoptotic process
positive regulation of epithelial cell apoptotic process
negative regulation of stem cell proliferation
protein phosphorylation
positive regulation of gene expression
negative regulation of cell growth
positive regulation of cell migration
negative regulation of cell migration
protein localization to cell surface
negative regulation of apoptotic process
positive regulation of protein kinase activity
negative regulation of transcription, DNA-templated
positive regulation of stress fiber assembly
negative regulation of cell death
positive regulation of protein kinase C signaling
cell-cell signaling
multicellular organism development
organ morphogenesis
positive regulation of GTPase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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