Search
Invitrogen
GNPDA1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 2
GNPDA1 Antibody (PA5-23236) in IHC (P)
Immunohistochemistry analysis of GNPDA1 in formalin-fixed paraffin-embedded human kidney tissue. Samples were incubated with GNPDA1 polyclonal antibody (Product # PA5-23236) using a dilution of 10 µg/mL. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Product Details
PA5-23236
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 100-150 of human GNPDA1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The amino acid sequence used as immunogen for the antibody is 88% homologous in Chicken, Zebrafish, and Xenopus.
Target Information
GNPDA1 is a 289 amino acid cytoplasmic protein belonging to the glucosamine/ galactosamine-6-phosphate isomerase family. It is one of the two mammalian glucosamine-6-phosphate deaminase enzymes. GNPDA1 is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate (GlcN6P) into D-fructose-6-phosphate (Fru6P) and ammonium with an aldo/keto isomerization and an amination/deamination. GNPDA1 may trigger calcium oscillations in mammalian eggs at fertilization which in turn serve as an important factor for egg development and early embryo development. It is a homohexamer, ubiquitously expressed in most of human tissues with high expression in testis, ovary, placenta, and heart and also in various cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GlcN6P deaminase 1; Glucosamine-6-phosphate deaminase 1; Glucosamine-6-phosphate isomerase 1; glucose-6-phosphate isomerase; GNPDA 1; KIAA0060; oscillin; Protein oscillin; sperm factor; unnamed protein product
Gene Aliases: GNP1; GNPDA; GNPDA1; GNPI; GPI; HLN; KIAA0060; oscillin
UniProt ID: (Human) P46926, (Mouse) O88958
Entrez Gene ID: (Human) 10007, (Mouse) 26384, (Rat) 683570
carbohydrate metabolic process
glucosamine catabolic process
N-acetylglucosamine metabolic process
N-acetylglucosamine catabolic process
UDP-N-acetylglucosamine biosynthetic process
generation of precursor metabolites and energy
single fertilization
N-acetylneuraminate catabolic process
fructose 6-phosphate metabolic process
glucosamine metabolic process
acrosome reaction
fructose biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support