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Invitrogen
IGF2BP1 Polyclonal Antibody
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FIGURE: 1 / 9
IGF2BP1 Antibody (PA5-23968) in ICC/IF
Immunofluorescence analysis of IGF2BP1 was performed using 70% confluent log phase Caco-2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with anti-IGF2BP1 Polyclonal Antibody (Product # PA5-23968) at 1:100 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Prod... View More
Product Details
PA5-23968
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 508-534 amino acids from the C-terminal region of human IGF2BP1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
200 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with chicken, mouse, rat and Xenopus and zebrafish based on sequence homology.
Target Information
IGF2BP1 is a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: coding region determinant binding protein; Coding region determinant-binding protein; CRD-BP; IGF-II mRNA-binding protein 1; IGF2 mRNA-binding protein 1; insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP; Insulin-like growth factor 2 mRNA-binding protein 1; insulin-like growth factor 2, binding protein 1; KH-domain containing protein; unnamed protein product; VICKZ family member 1; VIon ChannelKZ1; ZBP-1; zipcode binding protein 1; Zipcode-binding protein 1
Gene Aliases: AL024068; AW549074; CRD-BP; CRDBP; D030026A21Rik; D11Moh40e; D11Moh45; IGF2BP1; IMP-1; IMP1; mir-3063; Neilsen; VICKZ1; ZBP-1; ZBP1
UniProt ID: (Human) Q9NZI8, (Mouse) O88477
Entrez Gene ID: (Human) 10642, (Mouse) 140486
regulation of cytokine production
RNA localization
regulation of translation
nervous system development
positive regulation of cell proliferation
regulation of mRNA stability involved in response to stress
negative regulation of translation
pallium cell proliferation in forebrain
mRNA transport
CRD-mediated mRNA stabilization
neuronal stem cell population maintenance
dendrite arborization
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
positive regulation of cytoplasmic translation
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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