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Invitrogen
AMH Polyclonal Antibody
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FIGURE: 1 / 3
AMH Antibody (PA5-26938) in IHC (P)
Immunohistochemistry analysis of AMH in paraformaldehyde-fixed, paraffin-embedded sections human cerebellum tissue. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6). Samples were incubated with AMH polyclonal antibody (Product # PA5-26938) using a dilution of 1:25 for 1 hours at 37°C followed by... View More
Product Details
PA5-26938
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 424-451 amino acids of human AMH
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140 kDa disulfide linked precursor that is cleaved to release the mature 30 kDa homodimer. Originally classified as a fetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AMH; Anti-Muellerian hormone; MIS; Muellerian-inhibiting factor; Muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance
Gene Aliases: AMH; MIF; MIS
UniProt ID: (Human) P03971, (Mouse) P27106
Entrez Gene ID: (Human) 268, (Mouse) 11705
preantral ovarian follicle growth
urogenital system development
Mullerian duct regression
cell-cell signaling
positive regulation of gene expression
positive regulation of NF-kappaB transcription factor activity
negative regulation of ovarian follicle development
ovarian follicle development
gonadal mesoderm development
sex determination
sex differentiation
gonad development
response to xenobiotic stimulus
cell differentiation
Leydig cell differentiation
development of primary male sexual characteristics
positive regulation of SMAD protein import into nucleus
anti-Mullerian hormone signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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