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Invitrogen
GPBB Polyclonal Antibody
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FIGURE: 1 / 7
GPBB Antibody (PA5-28022) in IHC (P)
GPBB Polyclonal Antibody detects GPBB protein at cytosol on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. GPBB Polyclonal Antibody (Product # PA5-28022) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-28022
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human GPBB. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse brain.
Predicted reactivity: Mouse (92%), Rat (91%), Zebrafish (85%), Chicken (86%), Sheep (92%), Rhesus Monkey (98%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: brain glycogen phosphorylase; Glycogen phosphorylase, brain form; MGC9213; phosphorylase, glycogen; brain; unnamed protein product
Gene Aliases: GPBB; PYGB
UniProt ID: (Human) P11216, (Mouse) Q8CI94
Entrez Gene ID: (Human) 5834, (Mouse) 110078
catalytic activity
phosphorylase activity
protein binding
glycogen phosphorylase activity
transferase activity
transferase activity, transferring glycosyl groups
pyridoxal phosphate binding
drug binding
carbohydrate binding
protein homodimerization activity
glycosyltransferase
transferase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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