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Invitrogen
HLTF Polyclonal Antibody
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Product Details
PA5-30173
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human HLTF. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.62 mg/mL
Amount
62 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HeLa.
Predicted reactivity: Bovine (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA-binding protein/plasminogen activator inhibitor 1 regulator; DNA-binding protein/plasminogen activator inhibitor-1 regulator; DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF; Helicase-like transcription factor; HIP116; HLTF; mem; RING finger protein 80; RING-type E3 ubiquitin transferase HLTF; SMARCA3; SNF2-like 3; Sucrose nonfermenting protein 2-like 3; sucrose nonfermenting-like 3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; unnamed protein product
Gene Aliases: HIP116; HIP116A; HLTF; HLTF1; RNF80; SMARCA3; SNF2L3; ZBU1
UniProt ID: (Human) Q14527
Entrez Gene ID: (Human) 6596
nucleotide binding
nucleic acid binding
DNA binding
single-stranded DNA binding
RNA binding
catalytic activity
helicase activity
protein binding
ATP binding
DNA-dependent ATPase activity
zinc ion binding
DNA translocase activity
transferase activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
ubiquitin protein ligase binding
metal ion binding
ubiquitin protein ligase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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