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Invitrogen
Phospho-alpha Synuclein (Tyr136) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-alpha Synuclein (Tyr136) Antibody (PA5-35661) in WB
Western blot analysis of Phospho-alpha Synuclein pTyr136 in mouse brain tissue lysates with a blocking peptide (lane 1) and no blocking peptide (lane 2) using a Phospho-alpha Synuclein pTyr136 polyclonal antibody (Product # PA5-35661).
Product Details
PA5-35661
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from human Synuclein- alpha around the phosphorylation site of Tyrosine 136
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
-20°C
Shipping conditions
Ambient
RRID
Product Specific Information
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
Target Information
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways. Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease. Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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