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Invitrogen
TAF11 Polyclonal Antibody
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Product Details
PA5-40488
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human TAF11 (aa 1-50).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: MDDAHESPSD KGGETGESDE TAAVPGDPGA TDTDGIPEET DGDADVDLKE
Sequence homology: Cow: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 83%; Rabbit: 92%; Rat: 100%
Target Information
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: TAF(II)28; TAF11; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa; TAFII-28; TATA box binding protein (TBP)-associated factor, RNA polymerase II, I, 28kD; TFIID subunit p30-beta; transcription initiation factor TFIID 28 kD subunit; Transcription initiation factor TFIID 28 kDa subunit; Transcription initiation factor TFIID subunit 11; unnamed protein product
Gene Aliases: MGC:15243; PRO2134; TAF11; TAF2I; TAFII28
UniProt ID: (Human) Q15544
Entrez Gene ID: (Human) 6882
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
mRNA transcription from RNA polymerase II promoter
positive regulation by host of viral transcription
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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