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Invitrogen
UPF3A Polyclonal Antibody
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Product Details
PA5-41904
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human UPF3A
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: QRYHVDDGRR HRAHHEPERL SRRSEDEQRW GKGPGQDRGK KGSQDSGAPG
Sequence homology: Human: 100%
Target Information
UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hUpf3; involved in NMD pathway; Nonsense mRNA reducing factor 3A; Regulator of nonsense transcripts 3A; unnamed protein product; Up-frameshift suppressor 3 homolog A; UPF3 regulator of nonsense transcripts homolog A
Gene Aliases: HUPF3A; RENT3A; UPF3; UPF3A
UniProt ID: (Human) Q9H1J1
Entrez Gene ID: (Human) 65110
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
in utero embryonic development
spermatogenesis
positive regulation of translation
mRNA transport
positive regulation of mRNA cis splicing, via spliceosome
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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