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Invitrogen
CHRNA9 Polyclonal Antibody
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Product Details
PA5-46826
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human CHRNA9 (aa 1-50).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: MNWSHSCISF CWIYFAASRL RAAETADGKY AQKLFNDLFE DYSNALRPVE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 93%; Rabbit: 100%; Zebrafish: 80%
Target Information
CHRNA9 is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor superfamily. CHRNA9 is a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. It is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. The protein is additionally expressed in keratinocytes, the pituitary gland, B-cells and T-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor, neuronal nicotinic, alpha-9 subunit; cholinergic receptor; cholinergic receptor, nicotinic alpha 9; cholinergic receptor, nicotinic, alpha 9 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 9; NACHR alpha 9; NACHR alpha-9; neuronal acetylcholine receptor protein, alpha-9 subunit; Neuronal acetylcholine receptor subunit alpha-9; nicotinic acetylcholine receptor subunit alpha 9; Nicotinic acetylcholine receptor subunit alpha-9
Gene Aliases: CHRNA9; HSA243342; NACHRA9
UniProt ID: (Human) Q9UGM1
Entrez Gene ID: (Human) 55584
transmembrane signaling receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
excitatory extracellular ligand-gated ion channel activity
calcium channel activity
protein binding
acetylcholine-gated cation channel activity
serotonin-gated cation channel activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
ion transport
cation transport
calcium ion transport
positive regulation of cytosolic calcium ion concentration
serotonin receptor signaling pathway
chemical synaptic transmission
response to auditory stimulus
ion transmembrane transport
regulation of membrane potential
inner ear morphogenesis
detection of mechanical stimulus involved in sensory perception of sound
membrane depolarization
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
negative regulation of ERK1 and ERK2 cascade
calcium ion transmembrane transport
acetylcholine receptor signaling pathway
ligand-gated ion channel signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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