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Invitrogen
MUM1L1 Polyclonal Antibody
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Product Details
PA5-54217
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MUM1L1. Recombinant protein control fragment (Product #RP-92147).
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Amount
70 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AVMSVHSAVK EESACVKDEK FAPPLSPLSS DMLIMPKALK EESEDTCLET LAVPSECSAF SENIEDPGEG PSNPCLDTSQ NQPSMESEMG AAACPGSCSR ECEVSFSASN PVWDYSHLMS SERNFQRLDF EELEEEGQAS DKSLLPSRI
Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 44%.
Target Information
The MUM1L1 (Melanoma Associated Antigen (Mutated) 1-Like 1) gene encodes a protein that is a member of the PWWP domain-containing family and is thought to be involved in chromatin organization and gene expression regulation. Located on chromosome Xq22.3, MUM1L1 shares homology with the oncogene MUM1, known for its roles in cancer biology, particularly in multiple myeloma and lymphomas. The PWWP domain of MUM1L1 is implicated in binding histone methylation marks, thereby influencing transcriptional activity. Although the precise biological function of MUM1L1 remains to be fully elucidated, its expression patterns suggest a role in cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: melanoma associated antigen (mutated) 1-like 1; MUM1 like 1; MUM1-like protein 1; Mutated melanoma-associated antigen 1-like protein 1; PWWP domain-containing DNA repair factor 3B; PWWP domain-containing protein MUM1L1; PWWP3B; unnamed protein product
Gene Aliases: MUM1L1; PWWP3B
UniProt ID: (Human) Q5H9M0
Entrez Gene ID: (Human) 139221
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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