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Invitrogen
CNOT8 Polyclonal Antibody
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Product Details
PA5-76334
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human CNOT8.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
CNOT8 (CCR4-NOT transcription complex subunit 8), also known as CALIF or POP2, is a 292 amino acid protein that localizes to both the nucleus and the cytoplasm and functions as part of the CCR-NOT complex. Expressed ubiquitously, CNOT8 plays a role in transcriptional regulation for a diverse set of processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAF1-like protein; CAF1-like protein; CCR4-NOT complex subunit; Caf1b; CAF2; CALIFp; CCR4-associated factor 8; CCR4-NOT transcription complex subunit 8; h CAF1-like protein; PGK promoter directed over production; unnamed protein product
Gene Aliases: 1500015I04Rik; 1810022F04Rik; AA536816; AU015770; AU043059; CAF1; Caf1b; CALIF; CNOT8; hCAF1; POP2
UniProt ID: (Human) Q9UFF9, (Mouse) Q9D8X5
Entrez Gene ID: (Human) 9337, (Mouse) 69125
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
regulation of translation
positive regulation of cell proliferation
gene silencing by RNA
mRNA cleavage involved in gene silencing by miRNA
positive regulation of mRNA catabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
RNA phosphodiester bond hydrolysis, exonucleolytic
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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