Search
Invitrogen
Cbl-b Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-76651
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human Cbl-b.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes a protein of unknown function. The protein contains a bromodomain, a sequence motif often found in transcriptional coactivators, and localizes to the nucleus in testis and several other cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Cas-Br-M (murine) ecotropic retroviral transforming sequence b; Casitas B-lineage lymphoma proto-oncogene b; Cbl proto-oncogene B, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase B; E3 ubiquitin-protein ligase CBL-B; RING finger protein 56; RING-type E3 ubiquitin transferase CBL-B; SH3-binding protein CBL-B; Signal transduction protein CBL-B; unnamed protein product
Gene Aliases: ADMIO3; AI429560; AI851073; Cbl-b; CBLB; Nbla00127; RNF56
UniProt ID: (Human) Q13191, (Mouse) Q3TTA7
Entrez Gene ID: (Human) 868, (Mouse) 208650
phosphotyrosine binding
ubiquitin-protein transferase activity
calcium ion binding
protein binding
zinc ion binding
transferase activity
receptor tyrosine kinase binding
metal ion binding
ubiquitin protein ligase activity
signal transducer activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
protein kinase binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ligase
metabolite interconversion enzyme
positive regulation of T cell anergy
T cell anergy
NLS-bearing protein import into nucleus
immune response
signal transduction
cell surface receptor signaling pathway
protein ubiquitination
regulation of signaling
regulation of cell adhesion
protein catabolic process
positive regulation of protein ubiquitination
intracellular signal transduction
CD4-positive, alpha-beta T cell proliferation
negative regulation of epidermal growth factor receptor signaling pathway
T cell activation
positive regulation of protein catabolic process
T cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
regulation of postsynaptic neurotransmitter receptor internalization
regulation protein catabolic process at postsynapse
negative regulation of CD4-positive, alpha-beta T cell proliferation
regulation of platelet-derived growth factor receptor-alpha signaling pathway
negative regulation of alpha-beta T cell proliferation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support