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Invitrogen
STAU2 Polyclonal Antibody
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FIGURE: 1 / 3
STAU2 Antibody (PA5-78473) in ICC/IF
STAU2 Polyclonal Antibody detects STAU2 protein by immunofluorescent analysis. Sample: DIV9 rat E18 primary cortical neurons were fixed in 4% paraformaldehyde at RT for 15 min. Green: STAU2 protein stained by STAU2 Polyclonal Antibody (Product # PA5-78473) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [GT886] diluted at 1:500. Blue: Fluoroshield with DAPI .
Product Details
PA5-78473
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human STAU2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.80 mg/mL
Amount
80 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: U87-MG
Predicted Reactivity: Zebrafish (81%), Chicken (88%), Bovine (97%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48. 5% and 59. 9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Double-stranded RNA-binding protein Staufen homolog 2; r-staufen protein; staufen 2; staufen homolog 2; staufen, RNA binding protein, homolog 2; unnamed protein product
Gene Aliases: 39K2; 39K3; STAU2
UniProt ID: (Human) Q9NUL3, (Mouse) Q8CJ67, (Rat) Q68SB1
Entrez Gene ID: (Human) 27067, (Mouse) 29819, (Rat) 171500
germ cell development
intracellular mRNA localization
regulation of actin cytoskeleton organization
cellular response to oxidative stress
protein localization to synapse
eye morphogenesis
regulation of filopodium assembly
positive regulation of synapse assembly
positive regulation of dendritic spine morphogenesis
anterograde dendritic transport of messenger ribonucleoprotein complex
positive regulation of long term synaptic depression
transport
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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