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Invitrogen
ABCB6 Polyclonal Antibody
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Product Details
PA5-78693
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB6 (818-842aa YADMWQLQQGQEETSEDTKPQTMER).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA whole cell, MCF-7 whole cell, A549 whole cell. IHC: Human Mammary Cancer Tissue.
Target Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ABC; ABC-type heme transporter ABCB6; ATP binding cassette subfamily B member 6 (Langereis blood group); ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); EST45597; FLJ22414; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; unnamed protein product
Gene Aliases: ABC; ABCB6; LAN; MTABC3; PRP; UMAT
UniProt ID: (Human) Q9NP58
Entrez Gene ID: (Human) 10058
porphyrin-containing compound metabolic process
porphyrin-containing compound biosynthetic process
heme B biosynthetic process
cellular copper ion homeostasis
cellular iron ion homeostasis
brain development
heme transport
tetrapyrrole metabolic process
iron ion transmembrane transport
heme transmembrane transport
heme metabolic process
skin development
transmembrane transport
cellular detoxification of cadmium ion
melanosome assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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